Use of comparative proteomics to identify potential cisplatin-resistance mechanisms in neuroblastoma
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comparative analysis of the use of hedges & emphatics in english and persian academic research articles of sociology & psychology
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15 صفحه اولUsing proteomics to identify potential therapeutic targets in platelets.
Proteomics has provided powerful new insights into the complex events of the anucleate platelet and has revealed many potential protein targets in the search for suitable agents for thrombotic disease. In the present study, we summarize recent proteomic approaches to analyse specific platelet subproteomes, such as the platelet releasate, the platelet phosphotyrosine proteome and characterizatio...
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Background and Aim: The military personnel face many stressors. This study aimed to identify coping mechanisms in the face of stressors in military personnel. Methods: This is a cross-sectional study and the sample was 384 of staffs affiliated to Iranian Navy Force, who were selected by cluster random sampling. Data collection tools were demographic questionnaire, a military stressors questionn...
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Neuropathic pain is a condition that causes major chronic pain in millions of people worldwide. The reasons that cause this pain to persist remain unclear, and treatment has been inhibited by a lack of understanding of the chemical basis of this pain. Researchers have recently implicated dimethylsphingosine (DMS) as a molecule that is associated with inducing neuropathic pain. The group, led by...
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The transcriptional co-activator Yes-associated protein (YAP) is essential for Hippo pathway-driven tumorigenesis in various cancers. However, the expression and function of YAP in neuroblastoma remains elusive. Here, we show that YAP was highly expressed in Neuroblastoma (NB) and expression levels correlated with advanced tumor staging. Knockdown of YAP significantly impaired neuroblastoma pro...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2018
ISSN: 0923-7534
DOI: 10.1093/annonc/mdy304.025